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Amiodarona HCl
Chemical Name | Amiodarone hydrochloride 2-Butyl-3-benzofuranyl-4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl ketone hydrochloride |
CAS Number | 19774-82-4 |
Molecular Formula | C25H29I2NO3.HCl;C25H30ClI2NO3 |
Molecular Weight | 681.78 |
Molecular Structure |
|
Packing | 25kg/Drum |
Capacity | 100mt/Year |
Storage | Kept In Closed Container,Protected From Light. |
Application | Amiodarone hydrochloride is the hydrochloride of amiodarone, used for the third class of antiarrhythmic drugs for the treatment and prevention of ventricular and supraventricular arrhythmias have direct dilating effects on coronary arteries and peripheral blood vessels; can affect thyroxine metabolism. |
SPECIFICATION
| Items | Specification |
| Appearance | White or almost white, fine crystalline powder |
| Solubility | |
| Water | Very slightly soluble |
| Methanol | Soluble |
| Ethanol | Sparingly soluble |
| Methylene Chloride | Freely soluble |
| Identification | |
Infrared Absorption | Meet the requirements |
Chlorides | Meet the requirements |
| Appearance Of Solution | Clear and NMT GY 5 or BY 5 |
| PH | 3.2~3.8 |
Related substance ( HPLC) | Impurity H(TCL)≤0.02 % |
Any Impurity≤0.10 % | |
Total Impurities≤0.50 % | |
Iodide（ppm) | ≤150 |
Loss on drying | ≤0.50 % |
Sulfated ash | ≤0.10 % |
Assay | 98.5 ~ 101.0 % |
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