一水达沙替尼
DASATINIB MONOHYDRATE
Chemical Name | N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide monohydrate |
CAS Number | 863127-77-9 |
Molecular Formula | C22H26ClN7O2S.H2Oa |
Molecular Weight | 506.02 |
Molecular Structure | |
Packing | 25kg/drum |
Capacity | Production on order |
Storage | Store in a tightly sealed container away from heat and direct light, and in a cool dry place. |
Application | Dasatinib is an oral multi- BCR/Abl and Src family tyrosine kinase inhibitor approved for first line use in patients with chronic myelogenous leukemia (CML)and Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL). |
SPECIFICATION
Items | Specification |
Appearance | A white powder |
Melting Point | 279 - 281℃ |
Residual Solvents | ≤0.1% |
Residue on Ignition | ≤0.1% |
Heavy Metals | ≤10ppm |
Related Substance | ≤0.5% |
Assay (HPLC) | ≥99% |
Standard | Factory Standard |